Cargando…

TRH Analog, Taltirelin Improves Motor Function of Hemi-PD Rats Without Inducing Dyskinesia via Sustained Dopamine Stimulating Effect

Thyrotropin-releasing hormone (TRH) and its analogs are able to stimulate the release of the endogenic dopamine (DA) in the central nervous system. However, this effect has not been tested in the Parkinson’s disease (PD), which is characterized by the DA deficiency due to the dopaminergic neurons lo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zheng, Cong, Chen, Guiqin, Tan, Yang, Zeng, Weiqi, Peng, Qiwei, Wang, Ji, Cheng, Chi, Yang, Xiaoman, Nie, Shuke, Xu, Yan, Zhang, Zhentao, Papa, Stella M., Ye, Keqiang, Cao, Xuebing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282053/ https://www.ncbi.nlm.nih.gov/pubmed/30555300 http://dx.doi.org/10.3389/fncel.2018.00417

Ejemplares similares

TRH Analog, Taltirelin Protects Dopaminergic Neurons From Neurotoxicity of MPTP and Rotenone
por: Zheng, Cong, et al.
Publicado: (2018)

Are thyrotropin‐releasing hormone (TRH) and analog taltirelin viable reversal agents of opioid‐induced respiratory depression?
por: Algera, Marieke Hyke, et al.
Publicado: (2022)

Levetiracetam Ameliorates L-DOPA-Induced Dyskinesia in Hemiparkinsonian Rats Inducing Critical Molecular Changes in the Striatum
por: Du, Huan, et al.
Publicado: (2015)

Antidyskinetic Effects of MEK Inhibitor Are Associated with Multiple Neurochemical Alterations in the Striatum of Hemiparkinsonian Rats
por: Chen, Guiqin, et al.
Publicado: (2017)

The Rodent Models of Dyskinesia and Their Behavioral Assessment
por: Peng, Qiwei, et al.
Publicado: (2019)

Bilateral Implantation of Shear Stress Modifier in ApoE Knockout Mouse Induces Cognitive Impairment and Tau Abnormalities
por: Nie, Shuke, et al.
Publicado: (2018)

Differential activating effects of thyrotropin-releasing hormone and its analog taltirelin on motor output to the tongue musculature in vivo
por: Liu, Wen-Ying, et al.
Publicado: (2020)

Taltirelin is a superagonist at the human thyrotropin-releasing hormone receptor
por: Thirunarayanan, Nanthakumar, et al.
Publicado: (2012)

7,8-Dihydroxyflavone Protects Nigrostriatal Dopaminergic Neurons from Rotenone-Induced Neurotoxicity in Rodents
por: Nie, Shuke, et al.
Publicado: (2019)

Cerebrotendinous xanthomatosis: a comprehensive review of pathogenesis, clinical manifestations, diagnosis, and management
por: Nie, Shuke, et al.
Publicado: (2014)

Rifaximin modulates TRH and TRH-like peptide expression throughout the brain and peripheral tissues of male rats
por: Pekary, Albert Eugene, et al.
Publicado: (2022)

[β-Glu(2)]TRH Is a Functional Antagonist of Thyrotropin-Releasing Hormone (TRH) in the Rodent Brain
por: Prokai-Tatrai, Katalin, et al.
Publicado: (2021)

LY354740 Reduces Extracellular Glutamate Concentration, Inhibits Phosphorylation of Fyn/NMDARs, and Expression of PLK2/pS129 α-Synuclein in Mice Treated With Acute or Sub-Acute MPTP
por: Tan, Yang, et al.
Publicado: (2020)

A resveratrol derivative modulates TRH and TRH‐like peptide expression throughout the brain and peripheral tissues of male rats
por: Pekary, Albert Eugene, et al.
Publicado: (2022)

Histological Correlates of Neuroanatomical Changes in a Rat Model of Levodopa-Induced Dyskinesia Based on Voxel-Based Morphometry
por: Zhang, Xiaoqian, et al.
Publicado: (2021)

Identification of Glucocorticoid Response Element of the Rat TRH gene
por: Lee, Gyu-Chun, et al.
Publicado: (1996)

Transcriptional profiling of fetal hypothalamic TRH neurons
por: Guerra-Crespo, Magdalena, et al.
Publicado: (2011)

β-Arrestin2 Is Critically Involved in the Differential Regulation of Phosphosignaling Pathways by Thyrotropin-Releasing Hormone and Taltirelin
por: Drastichova, Zdenka, et al.
Publicado: (2022)

ODP297 Analysis of the responsible region of TRH in the hypothalamus-pituitary-thyroid axis using the Paraventricular nucleus-specific TRH deficient mice.
por: Kondo, Yuri, et al.
Publicado: (2022)

Levodopa-Induced Dyskinesia Is Associated with Increased Thyrotropin Releasing Hormone in the Dorsal Striatum of Hemi-Parkinsonian Rats
por: Cantuti-Castelvetri, Ippolita, et al.
Publicado: (2010)

TrhOnt: building an ontology to assist rehabilitation processes
por: Berges, Idoia, et al.
Publicado: (2016)

Hypothalamic TRH Mediates Anorectic Effects of Serotonin in Rats
por: Chávez, Jorge, et al.
Publicado: (2022)

Biochemical and physiological insights into TRH receptor-mediated signaling
por: Trubacova, Radka, et al.
Publicado: (2022)

Optical and pharmacological manipulation of hypoglossal motor nucleus identifies differential effects of taltirelin on sleeping tonic motor activity and responsiveness
por: Aggarwal, Jasmin, et al.
Publicado: (2023)

Analysis of Hypothalamic TRH Neurons in Regulating Thyroid Hormone Levels
por: Costa e Sousa, Ricardo H, et al.
Publicado: (2021)

Dopamine-Depleted Dopamine Transporter Knockout (DDD) Mice: Dyskinesia with L-DOPA and Dopamine D1 Agonists
por: Pogorelov, Vladimir M., et al.
Publicado: (2023)

Genetic characterization of trh positive Vibrio spp. isolated from Norway
por: Ellingsen, Anette B., et al.
Publicado: (2013)

Regionalized differentiation of CRH, TRH, and GHRH peptidergic neurons in the mouse hypothalamus
por: Morales-Delgado, Nicanor, et al.
Publicado: (2013)

Characterization of trh2 Harbouring Vibrio parahaemolyticus Strains Isolated in Germany
por: Bechlars, Silke, et al.
Publicado: (2015)

TRH site-specific methylation in oral and oropharyngeal squamous cell carcinoma
por: Puttipanyalears, C., et al.
Publicado: (2018)

Characterization and CRISPR-based genotyping of clinical trh-positive Vibrio parahaemolyticus
por: Kongrueng, Jetnapang, et al.
Publicado: (2018)

TRH-induced secretion of adrenocorticotropin and cortisol in dogs with pituitary-dependent hypercortisolism
por: Pijnacker, Tera, et al.
Publicado: (2018)

New Efforts to Demonstrate the Successful Use of TRH as a Therapeutic Agent
por: Alvarez-Salas, Elena, et al.
Publicado: (2023)

Maladaptive Plasticity in Levodopa-Induced Dyskinesias and Tardive Dyskinesias: Old and New Insights on the Effects of Dopamine Receptor Pharmacology
por: Cerasa, Antonio, et al.
Publicado: (2014)

Hemi-Hyperkinesis
por: Rostowski, J., et al.
Publicado: (1950)

Hemi-paraplegia and hemi-anaesthesia in the inflammatory bowel disease clinic
por: Ahmadi Nooredinvand, Hesam, et al.
Publicado: (2021)

Correction: Characterization of trh2 Harbouring Vibrio parahaemolyticus Strains Isolated in Germany
Publicado: (2015)

Pituitary Gangliocytoma Producing TSH and TRH: A Review of “Gangliocytomas of the Sellar Region”
por: Sakata, Kiyohiko, et al.
Publicado: (2020)

L-dopa-induced dyskinesia: beyond an excessive dopamine tone in the striatum
por: Porras, Gregory, et al.
Publicado: (2014)

Dopamine pathway and Parkinson's risk variants are associated with levodopa-induced dyskinesia
por: Sosero, Yuri L., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_mknv11r81sp67c0l7ooqgneulc