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Deconstructing internal ribosome entry site elements: an update of structural motifs and functional divergences

Beyond the general cap-dependent translation initiation, eukaryotic organisms use alternative mechanisms to initiate protein synthesis. Internal ribosome entry site (IRES) elements are cis-acting RNA regions that promote internal initiation of translation using a cap-independent mechanism. However,...

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Detalles Bibliográficos
Autores principales: Lozano, Gloria, Francisco-Velilla, Rosario, Martinez-Salas, Encarnacion
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282068/
https://www.ncbi.nlm.nih.gov/pubmed/30487301
http://dx.doi.org/10.1098/rsob.180155