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Cardiac and skeletal actin substrates uniquely tune cardiac myosin strain-dependent mechanics
Cardiac ventricular myosin (βmys) translates actin by transducing ATP free energy into mechanical work during muscle contraction. Unitary βmys translation of actin is the step-size. In vitro and in vivo βmys regulates contractile force and velocity autonomously by remixing three different step-sizes...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282072/ https://www.ncbi.nlm.nih.gov/pubmed/30463911 http://dx.doi.org/10.1098/rsob.180143 |