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Cardiac and skeletal actin substrates uniquely tune cardiac myosin strain-dependent mechanics

Cardiac ventricular myosin (βmys) translates actin by transducing ATP free energy into mechanical work during muscle contraction. Unitary βmys translation of actin is the step-size. In vitro and in vivo βmys regulates contractile force and velocity autonomously by remixing three different step-sizes...

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Detalles Bibliográficos
Autores principales:	Wang, Yihua, Ajtai, Katalin, Burghardt, Thomas P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282072/ https://www.ncbi.nlm.nih.gov/pubmed/30463911 http://dx.doi.org/10.1098/rsob.180143

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