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Sulfotransferase and Heparanase: Remodeling Engines in Promoting Virus Infection and Disease Development

An extraordinary binding site generated in heparan sulfate (HS) structures, during its biosynthesis, provides a unique opportunity to interact with multiple protein ligands including viral proteins, and therefore adds tremendous value to this master molecule. An example of such a moiety is the sulfa...

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Detalles Bibliográficos
Autores principales: Kaltenbach, Dominik D., Jaishankar, Dinesh, Hao, Meng, Beer, Jacob C., Volin, Michael V., Desai, Umesh R., Tiwari, Vaibhav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282075/
https://www.ncbi.nlm.nih.gov/pubmed/30555321
http://dx.doi.org/10.3389/fphar.2018.01315