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Anti-TNF-α Therapy Suppresses Proinflammatory Activities of Mucosal Neutrophils in Inflammatory Bowel Disease

Neutrophils have been found to play an important role in the pathogenesis of inflammatory bowel disease (IBD), and anti-TNF-α mAb (i.e., infliximab) therapy is demonstrated to be effective in the induction of clinical remission and mucosal healing in these patients. However, how anti-TNF-α mAb regul...

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Detalles Bibliográficos
Autores principales: Zhang, Cui, Shu, Weigang, Zhou, Guangxi, Lin, Jian, Chu, Feifei, Wu, Huili, Liu, Zhanju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282128/
https://www.ncbi.nlm.nih.gov/pubmed/30595666
http://dx.doi.org/10.1155/2018/3021863