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The Chaperone and Redox Properties of CnoX Chaperedoxins Are Tailored to the Proteostatic Needs of Bacterial Species

Hypochlorous acid (bleach), an oxidizing compound produced by neutrophils, turns the Escherichia coli chaperedoxin CnoX into a powerful holdase protecting its substrates from bleach-induced aggregation. CnoX is well conserved in bacteria, even in non-infectious species unlikely to encounter this oxi...

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Detalles Bibliográficos
Autores principales: Goemans, Camille V., Beaufay, François, Arts, Isabelle S., Agrebi, Rym, Vertommen, Didier, Collet, Jean-François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282202/
https://www.ncbi.nlm.nih.gov/pubmed/30482828
http://dx.doi.org/10.1128/mBio.01541-18