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STON2 negatively modulates stem-like properties in ovarian cancer cells via DNMT1/MUC1 pathway

BACKGROUND: Cancer stem cells (CSCs) possess abilities of self-renewal and differentiation, have oncogenic potential and are regarded to be the source of cancer recurrence. However, the mechanism by which CSCs maintain their stemness remains largely unclear. METHODS: In this study, the cell line-der...

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Detalles Bibliográficos
Autores principales: Xu, Shanshan, Yue, Yongfang, Zhang, Songfa, Zhou, Caiyun, Cheng, Xiaodong, Xie, Xing, Wang, Xinyu, Lu, Weiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282299/
https://www.ncbi.nlm.nih.gov/pubmed/30518424
http://dx.doi.org/10.1186/s13046-018-0977-y