Different mutational characteristics of the subsets of EGFR-tyrosine kinase inhibitor sensitizing mutation-positive lung adenocarcinoma

BACKGROUND: A subset of lung adenocarcinoma with EGFR-tyrosine kinase inhibitor sensitizing mutations (mEGFR) is common in non-smokers and women, suggesting that mutational stressors other than smoking are involved. METHODS: Targeted sequencing using a custom panel containing 70 cancer-related genes...

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Detalles Bibliográficos
Autores principales: Kim, Eun Young, Kim, Arum, Lee, Gaeun, Lee, Hangsuck, Chang, Yoon Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282318/
https://www.ncbi.nlm.nih.gov/pubmed/30522449
http://dx.doi.org/10.1186/s12885-018-5116-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282318/
https://www.ncbi.nlm.nih.gov/pubmed/30522449
http://dx.doi.org/10.1186/s12885-018-5116-9

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