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Oncolytic herpes simplex virus tumor targeting and neutralization escape by engineering viral envelope glycoproteins
Oncolytic herpes simplex viruses (oHSVs) have been approved for clinical usage and become more and more popular for tumor virotherapy. However, there are still many issues for the oHSVs used in clinics and clinical trials. The main issues are the limited anti-tumor effects, intratumor injection, and...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282442/ https://www.ncbi.nlm.nih.gov/pubmed/30799657 http://dx.doi.org/10.1080/10717544.2018.1534895 |