Homotypic and Heterotypic Activation of the Notch Pathway in Multiple Myeloma–Enhanced Angiogenesis: A Novel Therapeutic Target?()

Interactions of multiple myeloma (MM) cells with endothelial cells (ECs) enhance angiogenesis and MM progression. Here, we investigated the role of Notch signaling in the cross talk between ECs and MM cells enabling angiogenesis. MMECs showed higher expression of Jagged1/2 ligands, of activated Notc...

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Detalles Bibliográficos
Autores principales: Saltarella, Ilaria, Frassanito, Maria Antonia, Lamanuzzi, Aurelia, Brevi, Arianna, Leone, Patrizia, Desantis, Vanessa, Di Marzo, Lucia, Bellone, Matteo, Derudas, Daniele, Ribatti, Domenico, Chiaramonte, Raffaella, Palano, Maria Teresa, Neri, Antonino, Mariggiò, Maria Addolorata, Fumarulo, Ruggiero, Dammacco, Franco, Racanelli, Vito, Vacca, Angelo, Ria, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2018
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282459/
https://www.ncbi.nlm.nih.gov/pubmed/30529074
http://dx.doi.org/10.1016/j.neo.2018.10.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282459/
https://www.ncbi.nlm.nih.gov/pubmed/30529074
http://dx.doi.org/10.1016/j.neo.2018.10.011

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