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Detection of alpha‐synuclein conformational variants from gastro‐intestinal biopsy tissue as a potential biomarker for Parkinson's disease

AIMS: Gastrointestinal (GI) α‐synuclein (aSyn) detection as a potential biomarker of Parkinson's disease (PD) is challenged by conflicting results of recent studies. To increase sensitivity and specificity, we applied three techniques to detect different conformations of aSyn in GI biopsies obt...

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Detalles Bibliográficos
Autores principales: Ruffmann, C., Bengoa‐Vergniory, N., Poggiolini, I., Ritchie, D., Hu, M. T., Alegre‐Abarrategui, J., Parkkinen, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282510/
https://www.ncbi.nlm.nih.gov/pubmed/29676021
http://dx.doi.org/10.1111/nan.12486