Signaling of free fatty acid receptors 2 and 3 differs in colonic mucosa following selective agonism or coagonism by luminal propionate

BACKGROUND: Propionate exhibits affinity for free fatty acid receptor 2 (FFA2, formerly GPR43) and FFA3 (GPR41). These two G protein‐coupled receptors (GPCRs) are expressed by enteroendocrine L cells that contain anorectic peptide YY (PYY) and glucagon‐like peptide 1 (GLP‐1), while FFA3 is also expr...

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Detalles Bibliográficos
Autores principales: Tough, Iain R., Forbes, Sarah, Cox, Helen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282569/
https://www.ncbi.nlm.nih.gov/pubmed/30136343
http://dx.doi.org/10.1111/nmo.13454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282569/
https://www.ncbi.nlm.nih.gov/pubmed/30136343
http://dx.doi.org/10.1111/nmo.13454

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