Antibody adsorption in protein‐A affinity chromatography – in situ measurement of nanoscale structure by small‐angle X‐ray scattering

Protein‐A chromatography is the most widely used chromatography step in downstream processing of antibodies. A deeper understanding of the influence of the surface topology on a molecular/nanoscale level on adsorption is essential for further improvement. It is not clear if the binding is homogenous...

Descripción completa

Detalles Bibliográficos
Autores principales: Plewka, Jacek, Silva, Gonçalo L., Tscheließnig, Rupert, Rennhofer, Harald, Dias‐Cabral, Cristina, Jungbauer, Alois, Lichtenegger, Helga C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Liquid Chromatography
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282589/
https://www.ncbi.nlm.nih.gov/pubmed/30240534
http://dx.doi.org/10.1002/jssc.201800776

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282589/
https://www.ncbi.nlm.nih.gov/pubmed/30240534
http://dx.doi.org/10.1002/jssc.201800776

Ejemplares similares