Rare genetic variation in mitochondrial pathways influences the risk for Parkinson's disease

Background: Mitochondrial dysfunction plays a key role in PD, but the underlying molecular mechanisms remain unresolved. We hypothesized that the disruption of mitochondrial function in PD is primed by rare, protein‐altering variation in nuclear genes controlling mitochondrial structure and function...

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Detalles Bibliográficos
Autores principales: Gaare, Johannes J., Nido, Gonzalo S., Sztromwasser, Paweł, Knappskog, Per M., Dahl, Olav, Lund‐Johansen, Morten, Maple‐Grødem, Jodi, Alves, Guido, Tysnes, Ole‐Bjørn, Johansson, Stefan, Haugarvoll, Kristoffer, Tzoulis, Charalampos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282592/
https://www.ncbi.nlm.nih.gov/pubmed/30256453
http://dx.doi.org/10.1002/mds.64

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282592/
https://www.ncbi.nlm.nih.gov/pubmed/30256453
http://dx.doi.org/10.1002/mds.64

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