Cargando…

Computational characterization of the binding mode between oncoprotein Ets‐1 and DNA‐repair enzymes

The Ets‐1 oncoprotein is a transcription factor that promotes target gene expression in specific biological processes. Typically, Ets‐1 activity is low in healthy cells, but elevated levels of expression have been found in cancerous cells, specifically related to tumor progression. Like the vast maj...

Descripción completa

Detalles Bibliográficos
Autores principales: de Ruyck, Jerome, Brysbaert, Guillaume, Villeret, Vincent, Aumercier, Marc, Lensink, Marc F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282593/
https://www.ncbi.nlm.nih.gov/pubmed/30019773
http://dx.doi.org/10.1002/prot.25578