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Computational characterization of the binding mode between oncoprotein Ets‐1 and DNA‐repair enzymes
The Ets‐1 oncoprotein is a transcription factor that promotes target gene expression in specific biological processes. Typically, Ets‐1 activity is low in healthy cells, but elevated levels of expression have been found in cancerous cells, specifically related to tumor progression. Like the vast maj...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282593/ https://www.ncbi.nlm.nih.gov/pubmed/30019773 http://dx.doi.org/10.1002/prot.25578 |