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Structural and biochemical characterization of Plasmodium falciparum Hsp70‐x reveals functional versatility of its C‐terminal EEVN motif

Plasmodium falciparum, the main agent of malaria expresses six members of the heat shock protein 70 (Hsp70) family. Hsp70s serve as protein folding facilitators in the cell. Amongst the six Hsp70 species that P. falciparum expresses, Hsp70‐x (PfHsp70‐x), is partially exported to the host red blood c...

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Detalles Bibliográficos
Autores principales: Mabate, Blessing, Zininga, Tawanda, Ramatsui, Lebogang, Makumire, Stanley, Achilonu, Ikechukwu, Dirr, Heini W., Shonhai, Addmore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282620/
https://www.ncbi.nlm.nih.gov/pubmed/30183110
http://dx.doi.org/10.1002/prot.25600