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MicroRNA-29b Mediates Lung Mesenchymal-Epithelial Transition and Prevents Lung Fibrosis in the Silicosis Model

Lung epithelial-mesenchymal transition (EMT) plays an important role in silicosis fibrosis. The reverse process of EMT is mesenchymal-epithelial transition (MET), which is viewed as an anti-EMT therapy and is a good target toward fibrosis. MicroRNAs (miRNAs) have emerged as potent regulators of EMT...

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Detalles Bibliográficos
Autores principales: Sun, Jingping, Li, Qiuyue, Lian, Ximeng, Zhu, Zhonghui, Chen, Xiaowei, Pei, Wanying, Li, Siling, Abbas, Ali, Wang, Yan, Tian, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282658/
https://www.ncbi.nlm.nih.gov/pubmed/30529807
http://dx.doi.org/10.1016/j.omtn.2018.10.017