TLR7‐let‐7 Signaling Contributes to Ethanol‐Induced Hepatic Inflammatory Response in Mice and in Alcoholic Hepatitis

BACKGROUND: Toll‐like receptor 7 (TLR7) is an endosomal TLR that is activated by single‐stranded RNA, including endogenous microRNAs (e.g., let‐7b). Increased hepatic expression of TLRs, microRNAs, and inflammatory mediators is linked to ethanol (EtOH) exposure and to alcoholic liver disease (ALD)....

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Detalles Bibliográficos
Autores principales: Massey, Veronica L., Qin, Liya, Cabezas, Joaquin, Caballeria, Juan, Sancho‐Bru, Pau, Bataller, Ramon, Crews, Fulton T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Pathology, Immunology and Development
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282707/
https://www.ncbi.nlm.nih.gov/pubmed/30103265
http://dx.doi.org/10.1111/acer.13871

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282707/
https://www.ncbi.nlm.nih.gov/pubmed/30103265
http://dx.doi.org/10.1111/acer.13871

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