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FKBP51 modulates steroid sensitivity and NFκB signalling: A novel anti‐inflammatory drug target

Steroid refractory inflammation is an unmet medical need in the management of inflammatory diseases. Thus, mechanisms, improving steroid sensitivity and simultaneously decreasing inflammation have potential therapeutic utility. The FK506‐binding protein 51 (FKBP51) is reported to influence steroid s...

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Detalles Bibliográficos
Autores principales: Kästle, Marc, Kistler, Barbara, Lamla, Thorsten, Bretschneider, Tom, Lamb, David, Nicklin, Paul, Wyatt, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282724/
https://www.ncbi.nlm.nih.gov/pubmed/30169894
http://dx.doi.org/10.1002/eji.201847699