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Incorporating physiologically relevant mobile phases in micellar liquid chromatography for the prediction of human intestinal absorption

Micellar liquid chromatography is a popular method used in the determination of a compound's lipophilicity. This study describes the use of the obtained micelle–water partition coefficient (log P (mw)) by such a method in the prediction of human intestinal absorption (HIA). As a result of the c...

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Detalles Bibliográficos
Autores principales: Shokry, Dina S., Waters, Laura J., Parkes, Gareth M. B., Mitchell, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282790/
https://www.ncbi.nlm.nih.gov/pubmed/30062715
http://dx.doi.org/10.1002/bmc.4351