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Incorporating physiologically relevant mobile phases in micellar liquid chromatography for the prediction of human intestinal absorption
Micellar liquid chromatography is a popular method used in the determination of a compound's lipophilicity. This study describes the use of the obtained micelle–water partition coefficient (log P (mw)) by such a method in the prediction of human intestinal absorption (HIA). As a result of the c...
Autores principales: | Shokry, Dina S., Waters, Laura J., Parkes, Gareth M. B., Mitchell, John C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282790/ https://www.ncbi.nlm.nih.gov/pubmed/30062715 http://dx.doi.org/10.1002/bmc.4351 |
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