The Broad Aryl Acid Specificity of the Amide Bond Synthetase McbA Suggests Potential for the Biocatalytic Synthesis of Amides

Amide bond formation is one of the most important reactions in pharmaceutical synthetic chemistry. The development of sustainable methods for amide bond formation, including those that are catalyzed by enzymes, is therefore of significant interest. The ATP‐dependent amide bond synthetase (ABS) enzym...

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Detalles Bibliográficos
Autores principales: Petchey, Mark, Cuetos, Anibal, Rowlinson, Benjamin, Dannevald, Stephanie, Frese, Amina, Sutton, Peter W., Lovelock, Sarah, Lloyd, Richard C., Fairlamb, Ian J. S., Grogan, Gideon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282839/
https://www.ncbi.nlm.nih.gov/pubmed/30035356
http://dx.doi.org/10.1002/anie.201804592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282839/
https://www.ncbi.nlm.nih.gov/pubmed/30035356
http://dx.doi.org/10.1002/anie.201804592

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