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Macrophage Raptor Deficiency-Induced Lysosome Dysfunction Exacerbates Nonalcoholic Steatohepatitis

BACKGROUND & AIMS: Nonalcoholic steatohepatitis (NASH) is an increasingly prevalent nonalcoholic fatty liver disease, characterized by inflammatory cell infiltration and hepatocellular damage. Mammalian target of rapamycin complex 1 (mTORC1) has been investigated extensively in the context of ca...

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Detalles Bibliográficos
Autores principales: Liu, Wenli, Ye, Chenji, Cheng, Qian, Zhang, Xuejiao, Yao, Liu, Li, Qi, Huang, Jing, Liu, Yajin, Zou, Zhengsheng, Wang, Hua, Yan, Jun, Zhu, Yi, Wang, Chunjiong, Ai, Ding
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282883/
https://www.ncbi.nlm.nih.gov/pubmed/30539788
http://dx.doi.org/10.1016/j.jcmgh.2018.09.011