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Macrophage Raptor Deficiency-Induced Lysosome Dysfunction Exacerbates Nonalcoholic Steatohepatitis

BACKGROUND & AIMS: Nonalcoholic steatohepatitis (NASH) is an increasingly prevalent nonalcoholic fatty liver disease, characterized by inflammatory cell infiltration and hepatocellular damage. Mammalian target of rapamycin complex 1 (mTORC1) has been investigated extensively in the context of ca...

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Detalles Bibliográficos
Autores principales:	Liu, Wenli, Ye, Chenji, Cheng, Qian, Zhang, Xuejiao, Yao, Liu, Li, Qi, Huang, Jing, Liu, Yajin, Zou, Zhengsheng, Wang, Hua, Yan, Jun, Zhu, Yi, Wang, Chunjiong, Ai, Ding
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282883/ https://www.ncbi.nlm.nih.gov/pubmed/30539788 http://dx.doi.org/10.1016/j.jcmgh.2018.09.011

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