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Polymerizing Like Mussels Do: Toward Synthetic Mussel Foot Proteins and Resistant Glues

A novel strategy to generate adhesive protein analogues by enzyme‐induced polymerization of peptides is reported. Peptide polymerization relies on tyrosinase oxidation of tyrosine residues to Dopaquinones, which rapidly form cysteinyldopa‐moieties with free thiols from cysteine residues, thereby lin...

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Detalles Bibliográficos
Autores principales: Horsch, Justus, Wilke, Patrick, Pretzler, Matthias, Seuss, Maximilian, Melnyk, Inga, Remmler, Dario, Fery, Andreas, Rompel, Annette, Börner, Hans G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282983/
https://www.ncbi.nlm.nih.gov/pubmed/30246912
http://dx.doi.org/10.1002/anie.201809587