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3-(Naphthalen-2-yl(propoxy)methyl)azetidine hydrochloride attenuates MPP+-induced cytotoxicity by regulating oxidative stress and mitochondrial dysfunction in SH-SY5Y cells

Parkinson’s disease (PD) is a common chronic neurodegenerative disease mainly caused by the death of dopaminergic neurons. However, no complete pharmacotherapeutic approaches are currently available for PD therapies. 1-methyl-4-phenylpyridinium (MPP(+))-induced SH-SY5Y neurotoxicity has been broadly...

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Detalles Bibliográficos
Autores principales: Yang, Seung-Ju, Yang, Ji Woong, Na, Jung-Min, Ha, Ji Sun, Choi, Soo Young, Cho, Sung-Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283030/
https://www.ncbi.nlm.nih.gov/pubmed/29966582
http://dx.doi.org/10.5483/BMBRep.2018.51.11.123