Myeloid Disease Mutations of Splicing Factor SRSF2 Cause G2‐M Arrest and Skewed Differentiation of Human Hematopoietic Stem and Progenitor Cells

Myeloid malignancies, including myelodysplastic syndromes, chronic myelomonocytic leukemia, and acute myeloid leukemia, are characterized by abnormal proliferation and differentiation of hematopoietic stem and progenitor cells (HSPCs). Reports on analysis of bone marrow samples from patients have re...

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Detalles Bibliográficos
Autores principales: Bapat, Aditi, Keita, Nakia, Martelly, William, Kang, Paul, Seet, Christopher, Jacobsen, Jeffery R., Stoilov, Peter, Hu, Chengcheng, Crooks, Gay M., Sharma, Shalini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2018
Materias:
Cancer Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283046/
https://www.ncbi.nlm.nih.gov/pubmed/30004607
http://dx.doi.org/10.1002/stem.2885

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283046/
https://www.ncbi.nlm.nih.gov/pubmed/30004607
http://dx.doi.org/10.1002/stem.2885

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