Cargando…

A practical guide to pre‐trial simulations for Bayesian adaptive trials using SAS and BUGS

It is often unclear what specific adaptive trial design features lead to an efficient design which is also feasible to implement. Before deciding on a particular design, it is generally advisable to carry out a simulation study to characterise the properties of candidate designs under a range of pla...

Descripción completa

Detalles Bibliográficos
Autores principales: Hansen, Christian Holm, Warner, Pamela, Walker, Allan, Parker, Richard A., Whitaker, Lucy, Critchley, Hilary O.D., Weir, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283249/
https://www.ncbi.nlm.nih.gov/pubmed/30215881
http://dx.doi.org/10.1002/pst.1897