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Estimating the Contribution of Proteasomal Spliced Peptides to the HLA-I Ligandome*

Spliced peptides are short protein fragments spliced together in the proteasome by peptide bond formation. True estimation of the contribution of proteasome-spliced peptides (PSPs) to the global human leukocyte antigen (HLA) ligandome is critical. A recent study suggested that PSPs contribute up to...

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Detalles Bibliográficos
Autores principales: Mylonas, Roman, Beer, Ilan, Iseli, Christian, Chong, Chloe, Pak, Hui-Song, Gfeller, David, Coukos, George, Xenarios, Ioannis, Müller, Markus, Bassani-Sternberg, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283289/
https://www.ncbi.nlm.nih.gov/pubmed/30171158
http://dx.doi.org/10.1074/mcp.RA118.000877