ZYH005, a novel DNA intercalator, overcomes all-trans retinoic acid resistance in acute promyelocytic leukemia

Despite All-trans retinoic acid (ATRA) has transformed acute promyelocytic leukemia (APL) from the most fatal to the most curable hematological cancer, there remains a clinical challenge that many high-risk APL patients who fail to achieve a complete molecular remission or relapse and become resista...

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Detalles Bibliográficos
Autores principales: Tong, Qingyi, You, Huijuan, Chen, Xintao, Wang, Kongchao, Sun, Weiguang, Pei, Yufeng, Zhao, Xiaodan, Yuan, Ming, Zhu, Hucheng, Luo, Zengwei, Zhang, Yonghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Chemical Biology and Nucleic Acid Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283422/
https://www.ncbi.nlm.nih.gov/pubmed/29554366
http://dx.doi.org/10.1093/nar/gky202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283422/
https://www.ncbi.nlm.nih.gov/pubmed/29554366
http://dx.doi.org/10.1093/nar/gky202

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