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A comprehensive catalog of predicted functional upstream open reading frames in humans

Upstream open reading frames (uORFs) latent in mRNA transcripts are thought to modify translation of coding sequences by altering ribosome activity. Not all uORFs are thought to be active in such a process. To estimate the impact of uORFs on the regulation of translation in humans, we first circumsc...

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Detalles Bibliográficos
Autores principales: McGillivray, Patrick, Ault, Russell, Pawashe, Mayur, Kitchen, Robert, Balasubramanian, Suganthi, Gerstein, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283423/
https://www.ncbi.nlm.nih.gov/pubmed/29562350
http://dx.doi.org/10.1093/nar/gky188