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A comprehensive catalog of predicted functional upstream open reading frames in humans
Upstream open reading frames (uORFs) latent in mRNA transcripts are thought to modify translation of coding sequences by altering ribosome activity. Not all uORFs are thought to be active in such a process. To estimate the impact of uORFs on the regulation of translation in humans, we first circumsc...
Autores principales: | McGillivray, Patrick, Ault, Russell, Pawashe, Mayur, Kitchen, Robert, Balasubramanian, Suganthi, Gerstein, Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283423/ https://www.ncbi.nlm.nih.gov/pubmed/29562350 http://dx.doi.org/10.1093/nar/gky188 |
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