Pold3 is required for genomic stability and telomere integrity in embryonic stem cells and meiosis

Embryonic stem cells (ESCs) and meiosis are featured by relatively higher frequent homologous recombination associated with DNA double strand breaks (DSB) repair. Here, we show that Pold3 plays important roles in DSB repair, telomere maintenance and genomic stability of both ESCs and spermatocytes i...

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Detalles Bibliográficos
Autores principales: Zhou, Zhongcheng, Wang, Lingling, Ge, Feixiang, Gong, Peng, Wang, Hua, Wang, Feng, Chen, Lingyi, Liu, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283425/
https://www.ncbi.nlm.nih.gov/pubmed/29447390
http://dx.doi.org/10.1093/nar/gky098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283425/
https://www.ncbi.nlm.nih.gov/pubmed/29447390
http://dx.doi.org/10.1093/nar/gky098

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