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Virus Reduction Neutralization Test: A Single-Cell Imaging High-Throughput Virus Neutralization Assay for Dengue

Vaccine immunogenicity and clinical efficacy are often assessed by the measure of serum-neutralizing antibodies. The present gold standard for detecting neutralizing antibodies against many viruses, including dengue, is the plaque/focus reduction neutralization test (P/FRNT). The FRNT is a cell-base...

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Detalles Bibliográficos
Autores principales: Whiteman, Melissa C., Bogardus, Leah, Giacone, Danila G., Rubinstein, Leonard J., Antonello, Joseph M., Sun, Dengyun, Daijogo, Sarah, Gurney, Kevin B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Tropical Medicine and Hygiene 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283513/
https://www.ncbi.nlm.nih.gov/pubmed/30350775
http://dx.doi.org/10.4269/ajtmh.17-0948