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The impact of a fine-scale population stratification on rare variant association test results

Population stratification is a well-known confounding factor in both common and rare variant association analyses. Rare variants tend to be more geographically clustered than common variants, because of their more recent origin. However, it is not yet clear if population stratification at a very fin...

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Detalles Bibliográficos
Autores principales: Persyn, Elodie, Redon, Richard, Bellanger, Lise, Dina, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283567/
https://www.ncbi.nlm.nih.gov/pubmed/30521541
http://dx.doi.org/10.1371/journal.pone.0207677