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Structural insight into substrate and product binding in an archaeal mevalonate kinase
Mevalonate kinase (MK) is a key enzyme of the mevalonate pathway, which produces the biosynthetic precursors for steroids, including cholesterol, and isoprenoids, the largest class of natural products. Currently available crystal structures of MK from different organisms depict the enzyme in its unb...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283576/ https://www.ncbi.nlm.nih.gov/pubmed/30521590 http://dx.doi.org/10.1371/journal.pone.0208419 |