Global analysis of erythroid cells redox status reveals the involvement of Prdx1 and Prdx2 in the severity of beta thalassemia

β-thalassemia is a worldwide distributed monogenic red cell disorder, characterized by an absent or reduced beta globin chain synthesis. The unbalance of alpha-gamma chain and the presence of pathological free iron promote severe oxidative damage, playing crucial a role in erythrocyte hemolysis, exa...

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Detalles Bibliográficos
Autores principales: Romanello, Karen S., Teixeira, Karina K. L., Silva, João Pedro M. O., Nagamatsu, Sheila T., Bezerra, Marcos André C., Domingos, Igor F., Martins, Diego A. P., Araujo, Aderson S., Lanaro, Carolina, Breyer, Carlos A., Ferreira, Regiane A., Franco-Penteado, Carla, Costa, Fernando F., Malavazi, Iran, Netto, Luis E. S., de Oliveira, Marcos A., Cunha, Anderson F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283586/
https://www.ncbi.nlm.nih.gov/pubmed/30521599
http://dx.doi.org/10.1371/journal.pone.0208316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283586/
https://www.ncbi.nlm.nih.gov/pubmed/30521599
http://dx.doi.org/10.1371/journal.pone.0208316

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