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Metabolic models and gene essentiality data reveal essential and conserved metabolism in prokaryotes
Essential metabolic reactions are shaping constituents of metabolic networks, enabling viable and distinct phenotypes across diverse life forms. Here we analyse and compare modelling predictions of essential metabolic functions with experimental data and thereby identify core metabolic pathways in p...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283598/ https://www.ncbi.nlm.nih.gov/pubmed/30444863 http://dx.doi.org/10.1371/journal.pcbi.1006556 |