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Insights into antitrypanosomal drug mode-of-action from cytology-based profiling

Chemotherapy continues to have a major impact on reducing the burden of disease caused by trypanosomatids. Unfortunately though, the mode-of-action (MoA) of antitrypanosomal drugs typically remains unclear or only partially characterised. This is the case for four of five current drugs used to treat...

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Detalles Bibliográficos
Autores principales: Thomas, James A., Baker, Nicola, Hutchinson, Sebastian, Dominicus, Caia, Trenaman, Anna, Glover, Lucy, Alsford, Sam, Horn, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283605/
https://www.ncbi.nlm.nih.gov/pubmed/30475806
http://dx.doi.org/10.1371/journal.pntd.0006980