Binding of the general anesthetic sevoflurane to ion channels

The direct-site hypothesis assumes general anesthetics bind ion channels to impact protein equilibrium and function, inducing anesthesia. Despite advancements in the field, a first principle all-atom demonstration of this structure-function premise is still missing. We focus on the clinically used s...

Descripción completa

Detalles Bibliográficos
Autores principales: Stock, Letícia, Hosoume, Juliana, Cirqueira, Leonardo, Treptow, Werner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283617/
https://www.ncbi.nlm.nih.gov/pubmed/30475796
http://dx.doi.org/10.1371/journal.pcbi.1006605

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283617/
https://www.ncbi.nlm.nih.gov/pubmed/30475796
http://dx.doi.org/10.1371/journal.pcbi.1006605

Ejemplares similares