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Mismatch repair deficiency and aberrations in the Notch and Hedgehog pathways are of prognostic value in patients with endometrial cancer

The aim of this study was to investigate the prognostic value of the Hedgehog (Gli, Patched-1, Shh, Smo) and Notch (Jag1, Notch2, Notch3) pathway members, in comparison to a panel of proteins (ER, PgR, HER2/neu, Ki67, p53, p16, PTEN and MMR) previously suggested to be involved in the pathogenesis of...

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Detalles Bibliográficos
Autores principales: Polychronidou, Genovefa, Kotoula, Vassiliki, Manousou, Kyriaki, Kostopoulos, Ioannis, Karayannopoulou, Georgia, Vrettou, Eleni, Bobos, Mattheos, Raptou, Georgia, Efstratiou, Ioannis, Dionysopoulos, Dimitrios, Chatzopoulos, Kyriakos, Lakis, Sotirios, Chrisafi, Sofia, Tsolakidis, Dimitrios, Papanikolaou, Alexios, Dombros, Nikolaos, Fountzilas, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283658/
https://www.ncbi.nlm.nih.gov/pubmed/30521558
http://dx.doi.org/10.1371/journal.pone.0208221