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Differential regulation of the sphere formation and maintenance of cancer-initiating cells of malignant mesothelioma via CD44 and ALK4 signaling pathways

Malignant mesothelioma (MM) has a poor prognosis and is largely resistant to standard treatments, so it is important to seek novel therapeutic strategies for this disease. Cancer-initiating cells (CICs) were previously identified in MM using stem cell-associated markers in combination with spheroid...

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Detalles Bibliográficos
Autores principales: Ohno, Yoshiya, Shingyoku, Serina, Miyake, Sakina, Tanaka, Aya, Fudesaka, Sena, Shimizu, Yuta, Yoshifuji, Ai, Yamawaki, Yuki, Yoshida, Sachiyo, Tanaka, Saya, Sakura, Kazuma, Tanaka, Toshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283855/
https://www.ncbi.nlm.nih.gov/pubmed/30061637
http://dx.doi.org/10.1038/s41388-018-0405-y