Structural assembly of the megadalton-sized receptor for intestinal vitamin B(12) uptake and kidney protein reabsorption

The endocytic receptor cubam formed by the 460-kDa protein cubilin and the 45-kDa transmembrane protein amnionless (AMN), is essential for intestinal vitamin B(12) (B(12)) uptake and for protein (e.g. albumin) reabsorption from the kidney filtrate. Loss of function of any of the two components ultim...

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Detalles Bibliográficos
Autores principales: Larsen, Casper, Etzerodt, Anders, Madsen, Mette, Skjødt, Karsten, Moestrup, Søren Kragh, Andersen, Christian Brix Folsted
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283879/
https://www.ncbi.nlm.nih.gov/pubmed/30523278
http://dx.doi.org/10.1038/s41467-018-07468-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283879/
https://www.ncbi.nlm.nih.gov/pubmed/30523278
http://dx.doi.org/10.1038/s41467-018-07468-4

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