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Structural assembly of the megadalton-sized receptor for intestinal vitamin B(12) uptake and kidney protein reabsorption
The endocytic receptor cubam formed by the 460-kDa protein cubilin and the 45-kDa transmembrane protein amnionless (AMN), is essential for intestinal vitamin B(12) (B(12)) uptake and for protein (e.g. albumin) reabsorption from the kidney filtrate. Loss of function of any of the two components ultim...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283879/ https://www.ncbi.nlm.nih.gov/pubmed/30523278 http://dx.doi.org/10.1038/s41467-018-07468-4 |