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TGF-β downregulation-induced cancer cell death is finely regulated by the SAPK signaling cascade
Transforming growth factor (TGF)-β signaling is increasingly recognized as a key driver in cancer. In progressive cancer tissues, TGF-β promotes tumor formation, and its increased expression often correlates with cancer malignancy. In this study, we utilized adenoviruses expressing short hairpin RNA...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283885/ https://www.ncbi.nlm.nih.gov/pubmed/30523245 http://dx.doi.org/10.1038/s12276-018-0189-8 |