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Endocytosis of Activated Muscarinic m2 Receptor (m2R) in Live Mouse Hippocampal Neurons Occurs via a Clathrin-Dependent Pathway

Our aim was to examine the dynamics of the muscarinic m2 receptor (m2R), a G-protein coupled receptor (GPCR), after agonist activation in living hippocampal neurons, and especially clathrin dependency endocytosis. We have previously shown that the m2R undergoes agonist-induced internalization in viv...

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Detalles Bibliográficos
Autores principales: Lambert, Lisa, Dubayle, David, Fafouri, Assia, Herzog, Etienne, Csaba, Zsolt, Dournaud, Pascal, El Mestikawy, Salah, Bernard, Véronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283979/
https://www.ncbi.nlm.nih.gov/pubmed/30555302
http://dx.doi.org/10.3389/fncel.2018.00450