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β-Elemene Synergizes With Gefitinib to Inhibit Stem-Like Phenotypes and Progression of Lung Cancer via Down-Regulating EZH2

The inhibitors for EGF receptor tyrosine kinase (EGFR-TKIs) such as gefitinib have been used as a standard treatment for non-small cell lung cancer (NSCLC), but the increasingly occurrence of drug resistance, the associated adverse effects and the enrichment of cancer stem cells significantly impede...

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Detalles Bibliográficos
Autores principales: Cheng, Haibo, Ge, Xiaoyin, Zhuo, Shiqin, Gao, Yanan, Zhu, Bo, Zhang, Junfeng, Shang, Wenbin, Xu, Dakang, Ge, Weihong, Shi, Liyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284059/
https://www.ncbi.nlm.nih.gov/pubmed/30555330
http://dx.doi.org/10.3389/fphar.2018.01413