Grxcr1 Promotes Hair Bundle Development by Destabilizing the Physical Interaction between Harmonin and Sans Usher Syndrome Proteins

Morphogenesis and mechanoelectrical transduction of the hair cell mechanoreceptor depend on the correct assembly of Usher syndrome (USH) proteins into highly organized macromolecular complexes. Defects in these proteins lead to deafness and vestibular areflexia in USH patients. Mutations in a non-US...

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Detalles Bibliográficos
Autores principales: Blanco-Sánchez, Bernardo, Clément, Aurélie, Fierro, Javier, Stednitz, Sarah, Phillips, Jennifer B., Wegner, Jeremy, Panlilio, Jennifer M., Peirce, Judy L., Washbourne, Philip, Westerfield, Monte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284068/
https://www.ncbi.nlm.nih.gov/pubmed/30380418
http://dx.doi.org/10.1016/j.celrep.2018.10.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284068/
https://www.ncbi.nlm.nih.gov/pubmed/30380418
http://dx.doi.org/10.1016/j.celrep.2018.10.005

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