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In situ administration of cytokine combinations induces tumor regression in mice

BACKGROUND: Recent advances in cancer immunotherapy suggest a possibility of harnessing the immune system to defeat malignant tumors, but the complex immunosuppressive microenvironment confines the therapeutic benefits to a minority of patients with solid tumors. METHODS: A lentivector-based inducib...

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Detalles Bibliográficos
Autores principales: Zhang, Jinyu, Jiang, Haochen, Zhang, Haiyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284351/
https://www.ncbi.nlm.nih.gov/pubmed/30297145
http://dx.doi.org/10.1016/j.ebiom.2018.09.050